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absoluteantibody免疫治療研究抗體目錄
針對(duì)參與共刺激和免疫細(xì)胞調(diào)節(jié)其他方面的蛋白質(zhì)的抗體是治療開(kāi)發(fā)人員特別感興趣的。有些已經(jīng)進(jìn)入臨床，還有更多正在開(kāi)發(fā)中。然而，免疫細(xì)胞信號(hào)傳導(dǎo)的許多方面仍然未知，研究人員需要更先進(jìn)的工具來(lái)挖掘這種潛力。Absolute Antibody 開(kāi)發(fā)了一系列針對(duì)臨床相關(guān)蛋白質(zhì)的重組工程抗體，包括當(dāng)前治療靶點(diǎn)的小鼠同源物。
| Catalog ID | Mouse Target | Antibody Clone | Original Antibody Format |
|---|---|---|---|
| Ab01052 | 4-1BB (CD137) | LOB12.3 | Rat IgG1 |
| Ab01054 | 4-1BBL (CD137L) | AT113-2 | Rat IgG1 |
| Ab00881 | 4-1BBL (CD137L) | TKS-1 | Rat IgG2a |
| Ab01027 | BTLA | HMBT-6B2 | Hamster IgG |
| Ab00670 | CD27 | LG.3A10 | Hamster IgG |
| Ab00895 | CD27 | RM27-3E5 | Rat IgG2a |
| Ab00286 | CD28 | E18 | Mouse IgG2b |
| Ab00285 | CD28 | D665 | Mouse IgG1 |
| Ab01109 | CD40 | 3/23 | Rat IgG2a |
| Ab01087 | CD40L (CD154) | MR1 | Hamster IgG |
| Ab00816 | CD70 | TAN 1-7 | Rat IgG2a |
| Ab01056 | CD70 | TAN1-6 | Rat IgG2a |
| Ab01028 | CD80 (B7-1) | RM80 | Rat IgG2a |
| Ab01029 | CD86 (B7-2) | PO.3 | Rat IgG2b |
| Ab01089 | CD153 | RM153 | Rat IgG2b |
| Ab01297 | CD96 | 6A6 | Rat IgG2a |
| Ab00894 | CTLA-4 | 9H10 | Hamster IgG2 |
| Ab01018 | CTLA-4 | 9D9 | Mouse IgG2b |
| Ab01088 | GAL-9 | RG9-35 | Rat IgG2a |
| Ab01060 | GITR | DTA-1 | Rat IgG2a |
| Ab00374 | GITR | YGITR 860.103.5 | Rat IgG2b |
| Ab00631 | GITR | YGITR765 | Rat IgG2b |
| Ab00630 | GITRL | YGL386 | Rat IgG1 |
| Ab01026 | HVEM | HMHV-1B18 | Hamster IgG |
| Ab00814 | ICOS | 7E.17G9 | Rat IgG2b |
| Ab00882 | ICOSL | HK5.3 | Rat IgG2a |
| Ab01295 | LAG3 | C9B7W | Rat IgG1 |
| Ab01295 | LAG3 | C9B7W | Rat IgG1 |
| Ab00110 | OX40 (CD134) | OX86 | Rat IgG1 |
| Ab00564 | OX40L | OX-89 | Rat IgG1 |
| Ab00813 | PD-1 | RMP1-14 | Rat IgG2a |
| Ab01017 | PD-1H (VISTA) | mam82 | Mouse IgG1 |
| Ab01016 | PD-1H (VISTA) | MH5A | Hamster IgG |
| Ab00373 | PD-L1 | YDC 127.1.1 | Rat IgG2a |
| Ab00883 | PD-L2 | TY25 | Rat IgG2a |
| Ab00875 | PDPN (MAP-Tag) | PMab-1 | Rat IgG2a |
| Ab00973 | TIGIT | 4D4 | Hamster IgG |
| Ab01258 | TIGIT | 1B4 | Mouse IgG1 |
| Ab01032 | TIM-1 | 3B3 | Rat IgG2a |
| Ab01110 | TIM-2 | RMT2-14 | Rat IgG2a |
| Ab01057 | TIM-3 | 2C12 | Rat IgG1 |
| Ab01058 | TIM-4 | 5G3 | Rat IgG1 |
| Ab01059 | TIM-4 | 3A1 | Rat IgG1 |
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